Question 1
Which enzyme is primarily responsible for synthesizing mRNA during transcription?
A. DNA Polymerase
B. RNA Polymerase
C. Helicase
D. Ligase
Question 2
What is the role of tRNA during translation?
A. Carrying amino acids to the ribosome
B. Forming peptide bonds between amino acids
C. Unwinding the DNA double helix
D. Adding a poly-A tail to mRNA
Question 3
Which of the following modifications occurs to mRNA before it leaves the nucleus?
A. Addition of introns
B. Removal of exons
C. Addition of a 5' cap and poly-A tail
D. Formation of peptide bonds
Question 4
What is the significance of codon-anticodon pairing during translation?
A. It determines the start of transcription
B. It ensures the correct amino acid is added to the polypeptide chain
C. It adds a poly-A tail to mRNA
D. It forms the secondary structure of proteins
Question 5
Which level of protein structure involves the formation of alpha helices and beta pleated sheets?
A. Primary
B. Secondary
C. Tertiary
D. Quaternary
Question 6
a) Explain the role of RNA polymerase in transcription and how promoters influence this process. [3]
b) Discuss the significance of the addition of a poly-A tail and a 5' cap to mRNA. [3]
Question 7
a) Describe the role of tRNA in translation and how codon-anticodon pairing is essential for this process. [3]
b) Explain the stages of initiation, elongation, and termination in translation. [4]
Question 8
a) Discuss the formation of alpha helices and beta-pleated sheets in the secondary structure of proteins. [3]
b) Explain how interactions in tertiary structure contribute to the final conformation of a protein and its function. [4]
Question 9
a) Describe the discovery of the DNA structure by Watson, Crick, Wilkins, and Franklin. [3]
b) Explain the importance of the antiparallel strands in the DNA double helix. [2]
c) Discuss the significance of DNA structure in information storage. [3]
Question 10
a) Differentiate between DNA and RNA in terms of their sugar components. [2]
b) Discuss the role of mRNA, tRNA, and rRNA in protein synthesis. [4]
c) Why does RNA contain uracil instead of thymine? [2]