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AQA A-Level Psychology Notes

5.4.1 The Influence of Genes and Neurochemistry on Behaviour

Genetics and Behaviour

Genotype and Phenotype

  • Genotype: The genetic makeup of an individual, encompassing all the genes inherited from one's parents. Genotype is a critical factor in determining potential traits and behaviours.

    • Alleles: Different forms of a gene. The combination of alleles inherited can significantly influence physical traits and behavioural tendencies.

    • Inherited Characteristics: Traits and predispositions for certain behaviours are often passed down from parents to offspring.

    • Genetic Predisposition: This refers to the increased likelihood of developing particular behaviours or disorders based on one's genetic makeup.

  • Phenotype: This represents the observable characteristics and behaviours of an individual.

    • Interaction with Environment: Phenotype results not just from genotype, but also from the interaction of genetic factors with environmental influences.

    • Epigenetics: The study of changes in gene expression caused by mechanisms other than changes in the underlying DNA sequence. This field examines how behaviour and environment can influence the way genes are activated or deactivated.

Genetic Influence on Behaviour

  • Twin Studies: One of the most informative methods for understanding genetic influences on behaviour. By comparing monozygotic (identical) twins, who share 100% of their genes, with dizygotic (fraternal) twins, who share about 50%, researchers can glean insights into the genetic basis of behaviour.

  • Adoption Studies: These studies are instrumental in separating the effects of genetics from the environment. By studying individuals who were adopted and raised apart from their biological parents, researchers can discern the influence of genetics on behaviour.

  • Heritability Estimates: These statistical measures indicate the extent to which variation in a particular trait within a population can be attributed to genetic differences. However, it's important to note that heritability does not apply to individuals but to variations within a group.

  • Limitations: Quantifying the genetic influence on complex behaviours like intelligence or personality is challenging. The interplay between genes and environmental factors, such as upbringing and cultural influences, adds to the complexity.

Neurochemistry and Behaviour

Understanding Neurotransmitters

  • Neurotransmitters: These are chemicals in the brain that transmit signals from one neuron to another. They play a pivotal role in regulating mood, arousal, and behaviour.

    • Serotonin: Often associated with mood regulation. Low levels of serotonin have been linked to depression.

    • Dopamine: This neurotransmitter is crucial in the brain's reward system. It is involved in motivation, pleasure, and also plays a role in addiction and schizophrenia.

    • Norepinephrine: Affects arousal and alertness, and its imbalance can lead to anxiety disorders.

Hormones and Behaviour

  • Hormones: These are chemical messengers produced by glands in the body. They play a significant role in influencing behaviour and emotional states.

    • Cortisol: Known as the stress hormone, it can affect mood, memory, and has a range of physical impacts.

    • Oxytocin: Often referred to as the 'love hormone', it plays a role in social bonding and relationships.

    • Testosterone and Estrogen: These sex hormones can influence aggression, mood, and sexual behaviour.

Brain-Behaviour Interactions

  • Neurotransmitter Systems: The brain contains several neurotransmitter systems, each playing a distinct role in regulating behaviour. For instance, the serotonergic system is involved in mood and emotion, while the dopaminergic system is key in reward and motivation.

  • Neuroplasticity: This refers to the brain's ability to reorganise itself by forming new neural connections throughout life, influenced by learning and experience. This adaptability is crucial for recovery from brain injuries and adapting to new situations or environments.

  • Brain Imaging Studies: Techniques such as functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET) scans have revolutionised our understanding of the brain. These tools allow researchers to observe the brain in action and understand how neurochemical processes relate to behaviour.

Psychopharmacology

  • Medication: Psychotropic drugs can significantly alter neurochemistry and, consequently, behaviour and mood.

  • Antidepressants: These medications typically modify levels of neurotransmitters like serotonin and norepinephrine to treat symptoms of depression.

  • Antipsychotics: Primarily targeting dopamine and other neurotransmitter systems, these drugs are used to manage symptoms of conditions like schizophrenia and bipolar disorder.

Challenges and Ethical Considerations

  • Determinism vs Free Will: The Biological Approach often raises questions about the extent to which our behaviour is predetermined by biological factors versus the role of free will and personal choice.

  • Ethical Implications: The use of genetic information and neurochemical interventions raises significant ethical concerns. Issues such as consent, privacy, and the potential for genetic discrimination are paramount.

  • Cultural Sensitivity: It's crucial to recognise that interpretations of genetic and neurochemical research can differ across cultures, and these differences must be respected and understood in a global context.

Research Methodologies

  • Experimental Designs: These are used to establish cause-and-effect relationships between biological variables and behaviour. Such studies often involve manipulating one variable to observe the effect on another variable.

  • Correlational Studies: These studies look at the relationship between different variables, like genetic markers and specific behavioural traits. However, they do not imply causation, only association.

  • Case Studies: Providing in-depth analysis of individuals or groups, case studies are invaluable in providing detailed information about rare or unique conditions and behavioural patterns.

Conclusion

In sum, the Biological Approach offers a critical perspective in psychology, highlighting the importance of genetic and neurochemical factors in shaping behaviour. This approach underscores the complex interplay between our biological makeup and our actions, emotions, and cognitive processes, providing key insights into the understanding and treatment of various psychological conditions.

FAQ

Epigenetics has revolutionised our understanding of how genotype and phenotype are related. It refers to changes in gene expression caused by mechanisms other than changes in the DNA sequence itself. These changes can occur due to environmental factors, lifestyle choices, and even psychological experiences. For example, exposure to stress or a nurturing environment can cause certain genes to be turned on or off, thereby influencing an individual's phenotype without altering their underlying genetic code. This means that even with a certain genetic predisposition, environmental factors can play a significant role in determining whether and how these genetic traits are expressed. This understanding helps explain why identical twins with the same genotype can exhibit different phenotypes, highlighting the dynamic interaction between genes and the environment.

Neurotransmitter imbalances are often central to the development and manifestation of various psychological disorders. For instance, a deficiency in serotonin, a key neurotransmitter involved in mood regulation, is commonly associated with depression. Similarly, imbalances in dopamine levels are linked to schizophrenia and Parkinson's disease; in schizophrenia, excess dopamine activity in certain brain areas contributes to hallucinations and delusions, while in Parkinson's, a lack of dopamine leads to motor control issues. Anxiety disorders are often related to imbalances in neurotransmitters like norepinephrine and GABA. Thus, understanding and correcting these imbalances through medication or other therapies is crucial in treating these disorders.

Genetic testing can provide insights into an individual's predisposition for certain behavioural tendencies or psychological conditions, but it is not definitive in predicting them. Behaviour and psychological conditions are influenced by a complex interplay of multiple genes and environmental factors. While certain genes have been linked to higher risks of conditions like schizophrenia, bipolar disorder, or depression, having these genes does not guarantee the development of these conditions. Moreover, environmental factors such as stress, trauma, and lifestyle choices play a significant role in the manifestation of these conditions. Therefore, genetic testing should be interpreted with caution, understanding its limitations and the significant influence of environmental factors.

Hormone imbalances can have profound effects on behaviour and mood. Hormones like cortisol, estrogen, testosterone, and thyroid hormones, when imbalanced, can lead to various psychological and behavioural changes. For example, elevated cortisol levels, often a result of chronic stress, can lead to symptoms of depression, anxiety, and memory problems. Imbalances in sex hormones, such as estrogen and testosterone, can affect mood swings, aggression, and cognitive function. Thyroid hormone imbalances can lead to mood disorders, with hyperthyroidism often causing anxiety, irritability, and restlessness, and hypothyroidism leading to depression and fatigue. Thus, maintaining hormonal balance is essential for psychological well-being and stable mood.

Neuroplasticity, the brain's ability to reorganize itself by forming new neural connections, is significant in understanding the impact of neurochemistry on behaviour. It demonstrates that the brain is not a static organ but is adaptable and can change in response to experiences, learning, and environmental factors. Neuroplasticity is influenced by neurochemical processes; for example, learning and memory involve changes in neurotransmitter levels and receptor sensitivity, which in turn affect synaptic strength. This adaptability is vital for recovery from brain injuries, coping with stress, and learning new skills. Neuroplasticity also underpins the effectiveness of certain therapies and medications that work by altering neurochemistry, leading to changes in behaviour and cognitive processes.

Practice Questions

Explain how neurotransmitters can influence human behaviour, providing specific examples.

Neurotransmitters play a crucial role in transmitting signals across neurons in the brain, thereby significantly influencing human behaviour. For instance, serotonin is key in mood regulation, and its imbalance is linked with depression. Dopamine, associated with the brain's reward system, affects motivation and pleasure. It is also implicated in addiction and schizophrenia due to its role in reward-seeking behaviours. Another neurotransmitter, norepinephrine, impacts arousal and alertness levels, with imbalances possibly leading to anxiety disorders. These examples illustrate the profound effect neurotransmitters have on various aspects of human behaviour, from emotional states to cognitive functions and mental health.

Discuss the importance of twin studies in understanding the genetic basis of behaviour.

Twin studies are instrumental in disentangling the genetic basis of behaviour. By comparing monozygotic (identical) twins, who share virtually the same genetic makeup, with dizygotic (fraternal) twins, who share about half of their genes, researchers can glean insights into how much behaviour is influenced by genetics. These studies have provided evidence for the heritability of various traits and behaviours, ranging from intelligence to personality. For example, if a behaviour is found to be more common in identical twins than in fraternal twins, this suggests a significant genetic component. Such studies highlight the interplay between genetics and environment in shaping behaviour.

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