Provide an example of the aldehyde and nitrile in the Strecker synthesis.

In the Strecker synthesis, an aldehyde and a nitrile are used to produce an amino acid.

The aldehyde used in the Strecker synthesis is typically formaldehyde or an aldehyde derivative, such as benzaldehyde. The nitrile used is usually potassium cyanide (KCN), although other nitriles can also be used. These reagents are combined with ammonia in the presence of an acid catalyst, such as hydrochloric acid (HCl), to produce an amino acid.

The reaction proceeds through a series of steps, beginning with the formation of an imine intermediate between the aldehyde and ammonia. The imine then reacts with the nitrile to form an alpha-amino nitrile, which is hydrolyzed to produce the desired amino acid.

The Strecker synthesis is a useful method for the synthesis of amino acids, which are important building blocks of proteins. It is also used in the production of pharmaceuticals and other organic compounds. However, the use of cyanide in the reaction can be hazardous and requires careful handling and disposal. Alternative methods, such as the Gabriel synthesis, have been developed to avoid the use of cyanide.

Study and Practice for Free

Trusted by 100,000+ Students Worldwide

Achieve Top Grades in your Exams with our Free Resources.

Practice Questions, Study Notes, and Past Exam Papers for all Subjects!

Need help from an expert?

4.93/5 based on525 reviews

The world’s top online tutoring provider trusted by students, parents, and schools globally.

Related Chemistry a-level Answers

    Read All Answers
    Loading...