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Strong acids and bases dissociate completely in aqueous solution, while weak acids and bases only partially dissociate.
Strong acids, such as hydrochloric acid, sulfuric acid, and nitric acid, have a high tendency to donate protons (H+ ions) to water molecules. This results in a high concentration of H+ ions in solution, making the solution acidic. Strong bases, such as sodium hydroxide and potassium hydroxide, have a high tendency to accept protons from water molecules, resulting in a high concentration of OH- ions in solution, making the solution basic.
In contrast, weak acids and bases only partially dissociate in aqueous solution. This means that only a fraction of the acid or base molecules donate or accept protons, resulting in a lower concentration of H+ or OH- ions in solution. Weak acids, such as acetic acid and carbonic acid, have a lower tendency to donate protons to water molecules, resulting in a less acidic solution. Weak bases, such as ammonia and methylamine, have a lower tendency to accept protons from water molecules, resulting in a less basic solution.
The strength of an acid or base is determined by its dissociation constant (Ka or Kb), which is a measure of the extent of dissociation in solution. Strong acids and bases have very high dissociation constants, while weak acids and bases have lower dissociation constants. Understanding the differences between strong and weak acids and bases is important in many areas of biology, including biochemistry and physiology.
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