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Amides are organic compounds containing a carbonyl group and a nitrogen atom, while amines are organic compounds containing a nitrogen atom and one or more alkyl groups.
Amides are formed by the reaction of a carboxylic acid with an amine, resulting in the loss of a water molecule. They have a planar structure due to the presence of a double bond between the carbon and oxygen atoms. Amides are commonly found in proteins and nucleic acids, and they can act as hydrogen bond acceptors and donors.
Amines, on the other hand, are classified as primary, secondary, or tertiary depending on the number of alkyl groups attached to the nitrogen atom. They can be synthesized by the reaction of a primary or secondary amine with an alkyl halide, or by the reduction of a nitro compound. Amines have a trigonal pyramidal structure and can act as weak bases due to the presence of a lone pair of electrons on the nitrogen atom.
In terms of chemical properties, amides are less basic than amines due to the electron-withdrawing effect of the carbonyl group. They also have a higher boiling point and are less volatile than amines due to the presence of hydrogen bonding between the amide molecules. Amines, on the other hand, have a lower boiling point and are more volatile due to their weaker intermolecular forces.
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