What is the difference between homologous and sister chromatids?

Homologous chromosomes are pairs of chromosomes that have the same genes in the same order. Sister chromatids are identical copies of a single chromosome.

Homologous chromosomes are pairs of chromosomes that are similar in size, shape, and gene content. They are inherited from each parent and carry the same genes in the same order, but may have different versions of those genes. During meiosis, homologous chromosomes pair up and exchange genetic material through a process called crossing over. This creates genetic diversity in the offspring. For more details on meiosis, see Meiosis.

Sister chromatids, on the other hand, are identical copies of a single chromosome that are produced during DNA replication. They are held together by a structure called the centromere and are separated during cell division. Each daughter cell receives one copy of each chromosome, ensuring that the genetic information is passed on accurately. You can learn more about this process in Cell Division.

The main difference between homologous chromosomes and sister chromatids is that homologous chromosomes are pairs of chromosomes that carry the same genes in the same order, while sister chromatids are identical copies of a single chromosome. Homologous chromosomes are involved in genetic diversity through crossing over during meiosis, while sister chromatids ensure accurate genetic information is passed on during cell division. For further reading on chromosome structure, visit Chromosome Structure.


A-Level Biology Tutor Summary: Homologous chromosomes are matching pairs from each parent, similar in genes but can have different versions, important for genetic diversity through crossing over in meiosis. Sister chromatids are exact duplicates of a chromosome, made during DNA replication, crucial for accurate genetic transfer in cell division. The key difference is homologous chromosomes enhance diversity, whereas sister chromatids ensure precise genetic inheritance. For more insights into natural selection and genetic variation, refer to Natural Selection Explained.

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